Authors
Leonarda Galiuto, Barbara Garramone, Antonio Scarà, Antonio G Rebuzzi, Filippo Crea, Giuseppe La Torre, Stefania Funaro, Mariapina Madonna, Francesco Fedele, Luciano Agati, AMICI Investigators
Publication date
2008/2/5
Journal
Journal of the American College of Cardiology
Volume
51
Issue
5
Pages
552-559
Publisher
American College of Cardiology Foundation
Description
Objectives
We sought to evaluate the value of the extent of microvascular damage as assessed with myocardial contrast echocardiography (MCE) in the prediction of left ventricular (LV) remodeling after ST-segment elevation myocardial infarction (STEMI) as compared with established clinical and angiographic parameters of reperfusion.
Background
Early identification of post-percutaneous coronary intervention microvascular dysfunction may help in tailoring appropriate pharmacological interventions in high-risk patients. The ideal method to establish effective microvascular reperfusion after percutaneous coronary intervention remains to be determined.
Methods
A total of 110 patients with first successfully reperfused STEMI were enrolled in the AMICI (Acute Myocardial Infarction Contrast Imaging) multicenter study. After reperfusion, peak creatine kinase, ST-segment reduction, and Thrombolysis In Myocardial …
Total citations
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