Authors
Fabio Cavallaro, Claudio Sandroni, Cristina Marano, Giuseppe La Torre, Alice Mannocci, Chiara De Waure, Giuseppe Bello, Riccardo Maviglia, Massimo Antonelli
Publication date
2010/9
Source
Intensive care medicine
Volume
36
Pages
1475-1483
Publisher
Springer-Verlag
Description
Purpose
To systematically review the published evidence on the ability of passive leg raising-induced changes in cardiac output (PLR-cCO) and in arterial pulse pressure (PLR-cPP) to predict fluid responsiveness.
Methods
MEDLINE, EMBASE and the Cochrane Database of Systematic Reviews were screened. Clinical trials on human adults published as full-text articles in indexed journals were included. Two authors independently used a standardized form to extract data about study characteristics and results. Study quality was assessed by using the QUADAS scale.
Results
Nine articles including a total of 353 patients were included in the final analysis. Data are reported as point estimate (95% confidence intervals). The pooled sensitivity and specificity of PLR-cCO were 89.4% (84.1–93.4%) and 91.4% (85.9–95.2 …
Total citations
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