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The objective of this chapter is to describe the quality characteristics of distillers dried grains with solubles (DDGS) and new technologies used to produce new fractionated corn co-products. Quality of a feedstuff can be defined in many ways, but as described in Webster’s dictionary, it is the degree of excellence or superiority. Since corn co-products from ethanol production are sources of nutrients, high quality can be described as containing a consistently high level of economically important nutrients (eg, energy, amino acids, and phosphorus) that are highly digestible for the animal. Another way of describing quality according to Webster’s dictionary is the peculiar and essential character of something. Most corn co-products are produced as a result of the fermentation process used to produce ethanol and contain residual yeast and perhaps other compounds, which may provide additional health and nutritional benefits beyond the nutrients they provide to the animal’s diet.