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As 5G and network function virtualization (NFV) are maturing, it becomes crucial to demonstrate their feasibility and benefits by means of vertical scenarios. While 5GPPP has identified smart manufacturing as one of the most important vertical industries, there is still a lack of specific, practical use cases.Using the experience from a large-scale manufacturing company, Weidmüller Group, we present a detailed use case that reflects the needs of real-world manufacturers. We also propose an architecture with specific network services and virtual network functions (VNFs) that realize the use case in practice. As a proof of concept, we implement the required services and deploy them on an emulation-based prototyping platform. Our experimental results indicate that a fully virtualized smart manufacturing use case is not only feasible but also reduces machine interconnection and configuration time and thus improves …