Authors
Gagan S Wig, Timothy O Laumann, Alexander L Cohen, Jonathan D Power, Steven M Nelson, Matthew F Glasser, Francis M Miezin, Abraham Z Snyder, Bradley L Schlaggar, Steven E Petersen
Publication date
2014/8/1
Journal
Cerebral cortex
Volume
24
Issue
8
Pages
2036-2054
Publisher
Oxford University Press
Description
We describe methods for parcellating an individual subject's cortical and subcortical brain structures using resting-state functional correlations (RSFCs). Inspired by approaches from social network analysis, we first describe the application of snowball sampling on RSFC data (RSFC-Snowballing) to identify the centers of cortical areas, subdivisions of subcortical nuclei, and the cerebellum. RSFC-Snowballing parcellation is then compared with parcellation derived from identifying locations where RSFC maps exhibit abrupt transitions (RSFC-Boundary Mapping). RSFC-Snowballing and RSFC-Boundary Mapping largely complement one another, but also provide unique parcellation information; together, the methods identify independent entities with distinct functional correlations across many cortical and subcortical locations in the brain. RSFC parcellation is relatively reliable within a subject scanned across …
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