Authors
Brian T Joyce, Tao Gao, Kalsea Koss, Yinan Zheng, Andres Cardenas, Jonathan Heiss, Allan Just, Kai Zhang, Linda Van Horn, Norrina Bai Allen, Philip Greenland, Sheldon Cohen, Penny Gordon-Larsen, Colter Mitchell, Sara McLanahan, Lisa Schneper, Daniel Notterman, Sheryl L Rifas-Shiman, Emily Oken, Marie-France Hivert, Robert Wright, Andrea Baccarelli, Donald Lloyd-Jones, Lifang Hou
Publication date
2022/6/1
Journal
International journal of epidemiology
Volume
51
Issue
3
Pages
870-884
Publisher
Oxford University Press
Description
Background
Both parental and neighbourhood socio-economic status (SES) are linked to poorer health independently of personal SES measures, but the biological mechanisms are unclear. Our objective was to examine these influences via epigenetic age acceleration (EAA)—the discrepancy between chronological and epigenetic ages.
Methods
We examined three USA-based [Coronary Artery Risk Disease in Adults (CARDIA) study, Fragile Families and Child Wellbeing Study (FFCWS) and Programming Research in Obesity, Growth, Environment and Social Stressors (PROGRESS)] and one Mexico-based (Project Viva) cohort. DNA methylation was measured using Illumina arrays, personal/parental SES by questionnaire and neighbourhood disadvantage from geocoded address. In CARDIA, we examined the most strongly associated personal, parental and …
Total citations
Scholar articles
BT Joyce, T Gao, K Koss, Y Zheng, A Cardenas… - International journal of epidemiology, 2022