Authors
Simone L Broer, Ben Willem J Mol, Dave Hendriks, Frank JM Broekmans
Publication date
2009/3/1
Source
Fertility and sterility
Volume
91
Issue
3
Pages
705-714
Publisher
Elsevier
Description
OBJECTIVE: To assess the value of antimullerian hormone (AMH) as a test to predict poor ovarian response and pregnancy occurrence after IVF and to compare it with the performance of the antral follicle count (AFC). DESIGN: A systematic review of existing literature and a meta-analysis were carried out. After a comprehensive search, studies were included if 2 × 2 tables for outcomes poor response and pregnancy in IVF patients in relation to AMH or AFC could be constructed. SETTING: Academic referral center for tertiary care. PATIENT(S): Cases indicated for IVF. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Poor response and nonpregnancy after IVF. RESULT(S): A total of 13 studies were found reporting on AMH and 17 on AFC. Because of heterogeneity among studies, calculation of a summary point estimate for sensitivity and specificity was not possible. However, for both tests summary …
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