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A systematic study of the auriferous quartz veins of the Val-d’Or vein field, Abitibi, Quebec, Canada, demonstrates that the C, O, S isotope composition of silicate, carbonate, borate, oxide, tungstate and sulphide minerals have a range in composition comparable to that previously determined for the whole Superior Province. The oxygen isotope composition of quartz from early quartz–carbonate auriferous veins ranges from 9.4 ‰ to 14.4 ‰ whereas later quartz-tourmaline-carbonate veins have δ¹⁸O_quartz values ranging from 9.2 ‰ to 13.8 ‰. Quartz-carbonate veins have carbonate (δ¹⁸O: 6.9–12.5 ‰; δ¹³C: −6.2– −1.9 ‰) and pyrite (δ³⁴S: 1.2 and 1.9 ‰) isotope compositions comparable to those of quartz-tourmaline-carbonate veins (δ¹⁸O: 7.9–11.7 ‰; δ¹³C: −8.0 – −2.4 ‰; δ³⁴S: 0.6–6.0 ‰). δ¹⁸O_quartz values in quartz-tourmaline-carbonate veins have a variance comparable to analytical uncertainty at …