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Outdoor ventilation is very important for a healthy and livable urban environment. It is strongly influenced by wind speed and direction, which in turn are affected by urban morphology. This paper first provides a detailed review of the literature for CFD studies of outdoor ventilation for generic urban configurations. The review indicates that there is a clear lack of studies for urban configurations where not all parallel streets have equal street widths. Next, the paper presents Computational Fluid Dynamics (CFD) simulations of outdoor ventilation for generic configurations with parallel streets of equal and unequal street widths. The 3D steady RANS equations with the standard k–ɛ model and the passive scalar transport equation are used to calculate the effective local mean age of air at pedestrian level as an indicator of pollutant removal efficiency. The study is based on grid-convergence analysis and on validation with …