Authors
Lynn Stothers
Publication date
2010/4
Journal
The Journal of Urology
Volume
183
Issue
4S
Pages
e625-e625
Publisher
Wolters Kluwer
Description
METHODS
150 complete SCI (92 male 58 female) were followed prospectively, annually, at a tertiary care teaching hospital with video urodynamics, serum creatinine (screat), eGFR (Cockcroft-Gault formula), and 24 hour creatinine clearance for a 10 year period according to a neurogenic bladder follow up protocol. Documentation included compliance, detrusor leak point pressure, volume of first detrusor overactivity, amplitude of the first and maximum detrusor contraction, reflux and demographics (level of lesion, form of bladder management, gender, and urinary tract infections). Multivariate and multiple regression analysis were used to analyze for risk factors associated with renal dysfunction. Correlation measures were used to compare measures of renal function.
RESULTS
24 hour creatinine clearance showed evidence of renal dysfunction on average 2 years prior to changes in screat in both the males and …