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METHODS

Twenty four adult patients with lower urinary tract dysfunction were devided into 2 groups, PBS/IC (4 male aged: 27.5±8 yrs) and non-PBS/IC (8 male and 12 female aged: 47.7±4.8 yrs) after standard diagnostic investigations. Detrusor oxygen saturation percentage (TSI%), a direct index of tissue metabolism, were studied in all subjects using a spatially-resolved (SR) NIRS instrument, simultaneous to UDS study. After one minute baseline measurement in supine rest position with empty bladder, the detrusor TSI% was recorded by the NIRS instument that was placed and fixed over the bladder. Statistical difference of the detrusor TSI% values between two groups were studied.

RESULTS

Mean resting values of detrusor TSI% were significantly different (P< 0.0005) between 2 groups (74.2%±4.9 in PBS/IC vs. 63.6%±5.5 in non-PBS/IC).

CONCLUSIONS

Noninvasive NIRS interrogation of the bladder …