Authors
Tianyuan Liu, Huiyuan Qiao, Zixu Wang, Xinyan Yang, Xianrun Pan, Yu Yang, Xiucai Ye, Tetsuya Sakurai, Hao Lin, Yang Zhang
Publication date
2024/4/11
Journal
Advanced Science
Pages
2400009
Description
Recent studies have revealed that numerous lncRNAs can translate proteins under specific conditions, performing diverse biological functions, thus termed coding lncRNAs. Their comprehensive landscape, however, remains elusive due to this field's preliminary and dispersed nature. This study introduces codLncScape, a framework for coding lncRNA exploration consisting of codLncDB, codLncFlow, codLncWeb, and codLncNLP. Specifically, it contains a manually compiled knowledge base, codLncDB, encompassing 353 coding lncRNA entries validated by experiments. Building upon codLncDB, codLncFlow investigates the expression characteristics of these lncRNAs and their diagnostic potential in the pan‐cancer context, alongside their association with spermatogenesis. Furthermore, codLncWeb emerges as a platform for storing, browsing, and accessing knowledge concerning coding lncRNAs within …
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