Authors
Ami Patel, Stephen Hasak, Benjamin Cassell, Matthew A Ciorba, Emily E Vivio, Mrudula Kumar, C Prakash Gyawali, Gregory S Sayuk
Publication date
2016/8
Journal
Alimentary pharmacology & therapeutics
Volume
44
Issue
3
Pages
246-258
Description
Background
Sleep disturbances are common, and perhaps are even more prevalent in irritable bowel syndrome (IBS).
Aims
To determine the effect of measured sleep on IBS symptoms the following day, IBS‐specific quality of life (IBS‐QOL) and non‐GI pain symptoms.
Methods
IBS patients' sleep patterns were compared to healthy individuals via wrist‐mounted actigraphy over 7 days. Daily bowel pain logs (severity, distress; 10‐point Likert) stool pattern (Bristol scale) and supporting symptoms (e.g. bloating, urgency; 5‐point Likert) were kept. Validated measures, including the GI Symptom Rating Scale‐IBS, Visceral Sensitivity Index, Pittsburgh Sleep Quality Index and the IBS‐Quality of Life were collected. Mediation analysis explored the relationship between sleep, mood and bowel symptoms.
Results
Fifty subjects (38.6 ± 1.0 years old, 44 female; 24 IBS and 26 healthy controls) completed sleep monitoring …
Scholar articles
Effects of disturbed sleep on gastrointestinal and somatic pain symptoms in irritable bowel syndrome
A Patel, S Hasak, B Cassell, MA Ciorba, EE Vivio… - Alimentary pharmacology & therapeutics, 2016