Authors
Sameer S Kadri, Junfeng Sun, Alexander Lawandi, Jeffrey R Strich, Lindsay M Busch, Michael Keller, Ahmed Babiker, Christina Yek, Seidu Malik, Janell Krack, John P Dekker, Alicen B Spaulding, Emily Ricotta, John H Powers III, Chanu Rhee, Michael Klompas, Janhavi Athale, Tegan K Boehmer, Adi V Gundlapalli, William Bentley, S Deblina Datta, Robert L Danner, Cumhur Y Demirkale, Sarah Warner
Publication date
2021/9
Journal
Annals of Internal Medicine
Volume
174
Issue
9
Pages
1240-1251
Publisher
American College of Physicians
Description
Background
Several U.S. hospitals had surges in COVID-19 caseload, but their effect on COVID-19 survival rates remains unclear, especially independent of temporal changes in survival.
Objective
To determine the association between hospitals' severity-weighted COVID-19 caseload and COVID-19 mortality risk and identify effect modifiers of this relationship.
Design
Retrospective cohort study. (ClinicalTrials.gov: NCT04688372)
Setting
558 U.S. hospitals in the Premier Healthcare Database.
Participants
Adult COVID-19–coded inpatients admitted from March to August 2020 with discharge dispositions by October 2020.
Measurements
Each hospital-month was stratified by percentile rank on a surge index (a severity-weighted measure of …
Total citations
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