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3nallmoleculerwzdellingof~ enzyme active sites, nota?. iLy, the dicgrgenbindirqtype3oo~~+~~(I) sitesfoundinha~‘ns, tyrosinases and laccases, kich are dmracterised by MN-ligated unsaturated cq+ ex! l? c. xmtres cd. 350 mapxt, has proued &uitfulin the elucidation of the mxhxiisni of suktrate reaqnitim, birrlirq, and reacticn 111. Wzpresmtherethe. syn~ s and characteris&. im ofasirrplety~~ 3 site mxkl,[CUq (pz),(crge), l (1)(figure l)> &Ad& incorpxates the I+ dof0r ligands p@ kzine(pz) and cyancquanidine (crqe) to achieve the amiate CkCU separation (pz), arid ti3 stabilise the unsaturated gecmtry ofthe cqqxtr atans (crqe)[%]. FLpimdar quantities of tetrakis (ac&mitrile) c~(l) tetrafluortiate,~ i&zUie and cyancqmidine me added tx~ dry ac&orzit~ ile. AFter di_ssolutioril, the so1vent wz5 remmzd in vacua leaving an oraqe rxkdue% &xS $ Ent wdshirq With dick~ oDm&? ane, yielded the tetiaflm* rate salt of (‘I) as a bright yellow …