Authors
Seyed Ali Ziai, Bagher Larijani, Shahin Akhoondzadeh, Hossein Fakhrzadeh, Arezoo Dastpak, Fatemeh Bandarian, Afsaneh Rezai, Hassanali Naghdi Badi, Tara Emami
Publication date
2005/11/14
Journal
Journal of ethnopharmacology
Volume
102
Issue
2
Pages
202-207
Publisher
Elsevier
Description
Psyllium is a bulk-forming laxative and is high in both fiber and mucilage. The beneficial effect of dietary fiber in the management of type II diabetes, has not been totally demonstrated. The purpose of this study was to determine the plasma-lowering effects of 5.1g b.i.d. of psyllium husk fiber, as an adjunct to dietary and drug therapy on lipid and glucose levels, in patients with type II diabetes. Patients were randomly selected from an outpatient clinic of primary care to participate in a double-blind placebo-controlled study in which Plantago ovata Forsk., or placebo was given in combination with their anti-diabetic drugs. Forty-nine subjects were included in the study that were given diet counseling before the study and then followed for 8 weeks in the treatment period. Fasting plasma glucose (FBS) was measured every 2 weeks, and total plasma cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C …
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