Authors
J Preston Mercer, Russell S Sobel, Jeffrey E Wessell, William A Vandergrift, Jonathan C Edwards, Zeke M Campbell
Publication date
2024/7/1
Journal
Epilepsy & Behavior
Volume
156
Pages
109810
Publisher
Academic Press
Description
Objective Laser interstitial thermal therapy (LITT) is an alternative to anterior temporal lobectomy (ATL) for the treatment of temporal lobe epilepsy that has been found by some to have a lower procedure cost but is generally regarded as less effective and sometimes results in a subsequent procedure. The goal of this study is to incorporate subsequent procedures into the cost and outcome comparison between ATL and LITT. Methods This single-center, retrospective cohort study includes 85 patients undergoing ATL or LITT for temporal lobe epilepsy during the period September 2015 to December 2022. Of the 40 patients undergoing LITT, 35%(N= 14) underwent a subsequent ATL. An economic cost model is derived, and difference in means tests are used to compare the costs, outcomes, and other hospitalization measures. Results Our model predicts that whenever the percentage of LITT patients undergoing …