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Objectives To determine the differential impact of gender and age on pathological internet use (PIU) in the island of Kos, birthplace of Hippokrates and cradle of Medicine. Methods We surveyed the entire teen population (aged 14-19) of the island of Kos for symptoms of Internet addiction using Young's brief diagnostic questionnaire (YDQ) and an expanded demographics questionnaire. The sample consisted of 1221 adolescents, 587 male and 634 females, with a similar age distribution among the sexes. Results One-hundred fourteen teens (11,3% of Internet users) were classified as possibly addicted to the Internet. Results indicate that gender plays a more significant role than age in Internet abuse; there is a distinct pattern among the sexes with the girls scoring lower scores in the YDQ in all ages (chi square=22.758, p< .001) with a marked difference in the 17-19 age range. Although the symptoms of PIU …