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In this work, we explore a new method of in‐situ joining of polymers to metals in injection molding to allow direct bonding between thermoplastic and metal parts. Such a method can integrate several downstream steps in product manufacture, allow optimal design of products and joints, and avoid adhesive application, assembly, and associated difficlties. A variety of process parameters and their effects upon the interface tensile strengths were examined. A full factorial experiment was conducted involving four of the critical process parameters identified. The effects upon tensile strength at break of the following process parameters were studied: (1) adherend surface temperature, (2) screw linear velocity, (3) bondline thickness, and (4) pack and hold pressure. The fracture surfaces and the thermoplastic metal interfaces were analyzed. The bonds fabricated with higher adherend surface temperatures have increased …