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The recent increase in cybersecurity threats and cyberattacks impact organizations at various levels, including business-critical processes, and compromises business continuation and organizations survival. The cybersecurity of the healthcare sector, considered in many countries as critical national infrastructure, is addressed with particular interest, and focus in this study.

We propose an integrated cybersecurity methodology and supporting tools for healthcare operational information systems. The artifact named Cyber.SCuris is developed to complement cyber threat intelligence and incident response life cycle and standards such as NIST SP800. The proposed methodology and supporting tools are designed to operate in critical networks and medical contexts, to detect unexpected behavior and prevent cybersecurity breaches in areas as sensitive as the clinical process of healthcare institutions operational …