Authors
Dinesh Aggarwal, Ben Warne, Aminu S Jahun, William L Hamilton, Thomas Fieldman, Louis Du Plessis, Verity Hill, Beth Blane, Emmeline Watkins, Elizabeth Wright, Grant Hall, Catherine Ludden, Richard Myers, Myra Hosmillo, Yasmin Chaudhry, Malte L Pinckert, Iliana Georgana, Rhys Izuagbe, Danielle Leek, Olisaeloka Nsonwu, Gareth J Hughes, Simon Packer, Andrew J Page, Marina Metaxaki, Stewart Fuller, Gillian Weale, Jon Holgate, Christopher A Brown, Cambridge Covid-19 testing Centre Orton Alexandra 13 Douthwaite Julie 13 Rees Steve 13 Brown Christopher 13 14 Clark Roger 14 Jones Daniel R. 14 Kuenzi Fred 14 Rankin Jennifer 14 Waddell Ian 14, Rob Howes, Duncan McFarlane, Gordon Dougan, Oliver G Pybus, Daniela De Angelis, Patrick H Maxwell, Sharon J Peacock, Michael P Weekes, Chris Illingworth, Ewan M Harrison, Nicholas J Matheson, Ian G Goodfellow
Publication date
2022/2/8
Journal
Nature Communications
Volume
13
Issue
1
Pages
751
Publisher
Nature Publishing Group UK
Description
Understanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the …
Total citations
Scholar articles
D Aggarwal, B Warne, AS Jahun, WL Hamilton… - Nature Communications, 2022