Authors
Jule Rutz, Jan-Hendrik Naendrup, Caroline Bruns, Annika Y Classen, Jon Salmanton-García, Harald Seifert, Rosanne Sprute, Jannik Stemler, Sarah V Walker, Oliver A Cornely, Blasius J Liss, Sibylle C Mellinghoff
Publication date
2024/4
Journal
JAC-Antimicrobial Resistance
Volume
6
Issue
2
Pages
dlae046
Publisher
Oxford University Press
Description
Objectives
To assess incidence rates of surgical site infections (SSI) by MRSA and to determine related factors and clinical outcome compared to MSSA, including country-specific, institutional and patient determinants.
Patients and methods
We performed a subgroup analysis of the Europe-wide SALT (NCT03353532) study population with MRSA SSI from 14 centres in France, Germany, Italy, Spain and the UK.
Results
An overall MRSA SSI incidence of 0.06% (n = 104) was found in 178 903 patients undergoing invasive surgery in 2016. Frequently observed comorbidities were chronic cardiovascular disease, diabetes and solid tumours. Compared to the overall MRSA SSI incidence, incidence rates were significantly higher in Spain (58 of 67 934 cases) and lower in Germany (16 of 46 443 cases; both P < 0.05). Centres with antibiotic stewardship …
Scholar articles
J Rutz, JH Naendrup, C Bruns, AY Classen… - JAC-Antimicrobial Resistance, 2024