Authors
Ioannis E Koutroubakis, Claudia Ramos-Rivers, Miguel Regueiro, Efstratios Koutroumpakis, Benjamin Click, Marc Schwartz, Jason Swoger, Leonard Baidoo, Jana G Hashash, Arthur Barrie, Michael A Dunn, David G Binion
Publication date
2015/7/1
Journal
Inflammatory bowel diseases
Volume
21
Issue
7
Pages
1587-1593
Publisher
Oxford University Press
Description
Background
Anti–tumor necrosis factor (TNF) agents are an important component of inflammatory bowel disease (IBD) treatment, but data on their influence on anemia, a frequent complication of IBD, are limited. The aim of this study was to evaluate the effect of anti-TNF agents on hemoglobin (Hb) levels in a large IBD cohort.
Methods
Prospectively collected demographic, clinical, laboratory, and treatment data from IBD patients who started anti-TNF treatment at a tertiary referral center during the years 2010 to 2012 were analyzed. Follow-up data including disease activity scores (Harvey–Bradshaw index or ulcerative colitis activity index), quality of life scores (short IBD questionnaire) completed at each visit, and laboratory data were analyzed. Data from the year of anti-TNF initiation (yr 0) to the following year (yr 1) were compared.
Results
A total of 430 IBD …
Scholar articles
IE Koutroubakis, C Ramos-Rivers, M Regueiro… - Inflammatory bowel diseases, 2015