Authors
Sebastian G Spain, Matthew I Gibson, Neil R Cameron
Publication date
2007/6/1
Source
Journal of Polymer Science Part A: Polymer Chemistry
Volume
45
Issue
11
Pages
2059-2072
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Glycopolymers are receiving increasing interest due to their application in areas, such as glycomics, medicine, biotechnology, sensors, and separation science. Consequently, new methods for their synthesis are constantly being developed, with an increasing emphasis on the preparation of well‐defined polymers and on the production of complex macromolecular architectures such as stars. This review covers recent developments in the synthesis of glycopolymers, with a particular emphasis on (i) the use of controlled radical polymerization to prepare well‐defined glycopolymers from unprotected monomers and (ii) postpolymerization modification strategies using reactive polymer precursors (including “click” reactions). Recent work on the production of glycosylated polypeptides, which are under investigation as mimics of naturally occurring glycoproteins, is also included. The authors offer some suggestions as to …
Total citations
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Scholar articles
SG Spain, MI Gibson, NR Cameron - Journal of Polymer Science Part A: Polymer Chemistry, 2007