Authors
Sheng-Chieh Chuang, Parthasarathy Gandeepan, Chien-Hong Cheng
Publication date
2013/11/15
Journal
Organic letters
Volume
15
Issue
22
Pages
5750-5753
Publisher
American Chemical Society
Description
An efficient and mechanistically interesting method for the synthesis of highly substituted isoquinolines by a Rh(III)-catalyzed hydrazone directed ortho C–H bond activation and annulation without an external oxidant is described. This reaction is accomplished via a C–C and C–N bond formation along with N–N bond cleavage.
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