Authors
Fiona L Dignan, Robert F Wynn, Nedim Hadzic, John Karani, Alberto Quaglia, Antonio Pagliuca, Paul Veys, Michael N Potter, Haemato‐oncology Task Force of the British Committee for Standards in Haematology and the British Society for Blood and Marrow Transplantation
Publication date
2013/11
Journal
British journal of haematology
Volume
163
Issue
4
Pages
444-457
Description
Summary of Key Recommendations
Diagnosis
- It is recommended that the diagnosis of veno‐occlusive disease (sinusoidal obstruction syndrome) [VOD (SOS)] be based primarily on established clinical criteria (modified Seattle or Baltimore criteria) (1A).
- Ultrasound imaging may be helpful in the exclusion of other disorders in patients with suspected VOD (SOS) (1C).
- It is recommended that liver biopsy be reserved for patients in whom the diagnosis of VOD (SOS) is unclear and there is a need to exclude other diagnoses (1C).
- It is recommended that liver biopsies are undertaken using the transjugular approach in order to reduce the risks associated with the procedure (1C).
- It is suggested that the role of plasminogen activator inhibitor 1 levels remains an area for further research but that these levels should not form part of the routine diagnostic work‐up for VOD (SOS) at present (2C).
Risk factors
- It is …
Scholar articles
FL Dignan, RF Wynn, N Hadzic, J Karani, A Quaglia… - British journal of haematology, 2013