Authors
Eirini Karyotaki, Orestis Efthimiou, Clara Miguel, Frederic Maas genannt Bermpohl, Toshi A Furukawa, Pim Cuijpers, Heleen Riper, Vikram Patel, Adriana Mira, Alan W Gemmil, Albert S Yeung, Alfred Lange, Alishia D Williams, Andrew Mackinnon, Anna Geraedts, Annemieke Van Straten, Björn Meyer, Cecilia Björkelund, Christine Knaevelsrud, Christopher G Beevers, Cristina Botella, Daniel R Strunk, David C Mohr, David D Ebert, David Kessler, Derek Richards, Elizabeth Littlewood, Erik Forsell, Fan Feng, Fang Wang, Gerhard Andersson, Heather Hadjistavropoulos, Heleen Christensen, Iony D Ezawa, Isabella Choi, Isabelle M Rosso, Jan Philipp Klein, Jason Shumake, Javier Garcia-Campayo, Jeannette Milgrom, Jessica Smith, Jesus Montero-Marin, Jill M Newby, Juana Bretón-López, Justine Schneider, Kristofer Vernmark, Lara Bücker, Lisa B Sheeber, Lisanne Warmerdam, Louise Farrer, Manuel Heinrich, Marcus JH Huibers, Marie Kivi, Martin Kraepelien, Nicholas R Forand, Nicky Pugh, Nils Lindefors, Ove Lintvedt, Pavle Zagorscak, Per Carlbring, Rachel Phillips, Robert Johansson, Ronald C Kessler, Sally Brabyn, Sarah Perini, Scott L Rauch, Simon Gilbody, Steffen Moritz, Thomas Berger, Victor Pop, Viktor Kaldo, Viola Spek, Yvonne Forsell
Publication date
2021/4/1
Source
JAMA psychiatry
Volume
78
Issue
4
Pages
361-371
Publisher
American Medical Association
Description
Importance
Personalized treatment choices would increase the effectiveness of internet-based cognitive behavioral therapy (iCBT) for depression to the extent that patients differ in interventions that better suit them.
Objective
To provide personalized estimates of short-term and long-term relative efficacy of guided and unguided iCBT for depression using patient-level information.
Data Sources
We searched PubMed, Embase, PsycInfo, and Cochrane Library to identify randomized clinical trials (RCTs) published up to January 1, 2019.
Study Selection
Eligible RCTs were those comparing guided or unguided iCBT against each other or against any control intervention in individuals with depression. Available individual patient data (IPD) was collected from all eligible studies. Depression symptom severity was assessed after treatment, 6 months, and 12 months after randomization.
Data Extraction and Synthesis
We …
Total citations
Scholar articles
E Karyotaki, O Efthimiou, C Miguel… - JAMA psychiatry, 2021