Authors
Guanxiong Li, Shouheng Sun, Robert J Wilson, Robert L White, Nader Pourmand, Shan X Wang
Publication date
2006/1/26
Journal
Sensors and Actuators A: Physical
Volume
126
Issue
1
Pages
98-106
Publisher
Elsevier
Description
We present giant magnetoresistance (GMR) spin valve sensors designed for detection of superparamagnetic nanoparticles as potential biomolecular labels in magnetic biodetection technology. We discuss the sensor design and experimentally demonstrate that as few as ∼23 monodisperse 16-nm superparamagnetic Fe3O4 nanoparticles can be detected by submicron spin valve sensors at room temperature without resorting to lock-in detection. A patterned self-assembly method of nanoparticles, based on a polymer-mediated process and fine lithography, is developed for the detection. It is found that sensor signal increases linearly with the number of nanoparticles.
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Scholar articles
G Li, S Sun, RJ Wilson, RL White, N Pourmand… - Sensors and Actuators A: Physical, 2006