View article

This paper describes a computer method to correct the shape of three-dimensional (3D) left ventricle (LV) models created from magnetic resonance imaging (MRI) data that is affected by patient motion during scanning. Three-dimensional meshes of the LV endocardial and epicardial surfaces are created from border-delineated MRI data at every time frame of the cardiac cycle to generate a time-series model of the heart. A geometrically-based approach is used to achieve smooth epicardial shapes by iterative in-plane translation of vertices in the LV model. The Principal Curvatures of the LV epicardial surfaces across multiple time frames are used to construct a shape-based optimization objective function to restore the shape of the LV via a dual-resolution semi-rigid deformation process and a free-form geometric deformation process. A limited memory quasi-Newton algorithm, L-BFGS-B, is then used to solve the …