Authors
Joanne Feeney, Neil O’Leary, Rachel Moran, Aisling M O’Halloran, John M Nolan, Stephen Beatty, Ian S Young, Rose Anne Kenny
Publication date
2017/10/1
Journal
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences
Volume
72
Issue
10
Pages
1431-1436
Publisher
Oxford University Press
Description
Background
Low blood serum or plasma concentrations of the xanthophyll carotenoids lutein and zeaxanthin have been implicated in poorer cognitive health in older adults. However, equivocal results from smaller studies and clinical trials highlight the need for large population-based studies with comprehensive measures of cognitive function and adjustment for multiple confounders to examine such associations in more depth.
Methods
In the current study, we investigated the association between plasma lutein and zeaxanthin and domain-specific cognitive performance in 4,076 community-dwelling adults aged 50 years or older from The Irish Longitudinal Study on Ageing. Mixed-effects models were fitted with adjustment for demographic and socioeconomic factors, health conditions, and health behaviors.
Results
Higher plasma lutein and zeaxanthin …
Total citations
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