Authors
Yang Lyu, Xinyu Lv, Weiping Liu, Martin S Judenhofer, Allison Zwingenberger, Erik R Wisner, Eric Berg, Sarah Eva McKenney, Edwin K Leung, Benjamin A Spencer, Simon R Cherry, Ramsey D Badawi
Publication date
2019/1/8
Journal
Physics in Medicine and Biology
Publisher
IOP Publishing
Description
As part of the EXPLORER total-body positron emission tomography (PET) project, we have designed and built a high-resolution, high-sensitivity PET/CT scanner, which is expected to have excellent performance for companion animal whole body and human brain imaging. The PET component has a ring diameter of 52 cm and an axial field of view of 48.3 cm. The detector modules are composed of arrays of lutetium (yttrium) oxyorthosilicate (LYSO) crystals of dimensions 2.76× 2.76× 18.1 mm 3 coupled to silicon photomultipliers (SiPMs) for read-out. The CT component is a 24 detector row CT scanner with a 50 kW x-ray tube. PET system time-of-flight resolution was measured to be 409±39 ps and average system energy resolution was 11.7%±1.5% at 511 keV. The NEMA NU2-2012 system sensitivity was found to be 52–54 kcps MBq− 1. Spatial resolution was 2.6 mm at 10 mm from the center of the FOV and 2.0 …
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