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Objective: This meta-analysis of randomized controlled trials (RCTs) on the Transcendental Meditation® (TM) technique updates previous meta-analyses and assesses the effects of initial anxiety level, age, duration of practice, regularity of practice, research quality, author affiliation, and type of control group on effect sizes.

Design: This systematic review of the literature used the Comprehensive Meta-Analysis (CMA) program for core analyses of effect sizes, bias analysis, meta-regression, and moderator variable analysis. Comprehensive literature searches included databases devoted to meditation research.

Results: More than 600 TM research papers were identified; 14 of these addressed trait anxiety and reported on 16 studies among 1295 participants with diverse demographic characteristics. No adverse effects were reported. The standardized difference in mean, d, for the TM technique compared with …