Authors
Bibhabasu Hazra, Rhitajit Sarkar, Sourav Mandal, Santanu Biswas, Nripendranath Mandal
Publication date
2009
Journal
African Journal of Biotechnology
Volume
8
Issue
16
Description
It has been proposed that free radicals are essential part of aerobic life and modulate various physiological functions (Halliwell, 1991). Normally they are generated at a low level but, sometimes, their excessive generation may disrupt the body’s antioxidant system which may lead to “oxidative stress”. This situation contributes to a variety of disorders including cancer, coronary heart disease, atherosclerosis, neurodegenerative disorders, diabetes, lung disease and inflammatory diseases (Marnett, 2000; Braca et al., 2002). However, antioxidants can prevent the free radical generation by reacting with them, chelating catalytic metals and also by playing as oxygen scavengers. Although the development of some synthetic antioxidants in the past few years has flourished, they are not yet widely used as therapeutic agents due to their possible toxicity. As a result of which the development of natural antioxidant has now
Total citations
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Scholar articles
B Hazra, R Sarkar, S Mandal, S Biswas, N Mandal - African Journal of Biotechnology, 2009