Authors
Santanu Biswas, Pradip K Ghoshal, Sankar C Mandal, Nripendranath Mandal
Publication date
2008/10/1
Journal
Journal of cardiology
Volume
52
Issue
2
Pages
118-126
Publisher
Elsevier
Description
BACKGROUND
Worldwide coronary heart disease (CHD) is estimated to be the leading cause of death. Current knowledge about prevention of CHD is mainly derived from developed countries. Therefore, this study aimed to find out the association of CHD with ratios of different lipoproteins and apolipoproteins, LDL particle size, as well as different traditional risk factors in Asian Indian population in Eastern part of India.
METHODS
Case–control study of 100 patients with CHD and 98 healthy controls were age and sex matched. After clinical evaluation, blood samples were collected for biochemical assays.
RESULTS
Multivariate logistic regression analysis found apoB (OR 2.96; 95% CI 1.02–8.54), apoB/HDL-c (OR 4.14; 95% CI 1.33–12.83), nonHDL-c (OR 5.41; 95% CI 2.08–14.10), apoB/apoAI (OR 6.64; 95% CI 2.37–18.57), and LDL particle size (9.59; 95% CI 2.92–31.54) were independently associated with …
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