Authors
Jon Barrett, Elizabeth Aztalos, Andy Willan, Ks Joseph, B Anthony Armson, Eileen Hutton, Alexander Allen, Arne Ohlsson, Sue Ross, Scott Farrell, Amiram Gafni, Nan Okun, Mary Hannah
Publication date
2013/1/1
Journal
American Journal of Obstetrics & Gynecology
Volume
208
Issue
1
Pages
S4-S5
Publisher
Elsevier
Description
Objective
To compare planned CS with planned VB for twins 320/7 to 386/7 weeks, if the first twin is cephalic.
Study Design
Prospective RCT. Eligibility: Twins 32 to 38+ 6weeks, live fetuses, Twin A cephalic, EFW 1500g-4000g. Exclusion: Fetal reduction at> 13 wks gestation, lethal fetal anomaly, contraindication to labour. Delivery planned between 375/7 to 386/7 weeks by CS or inducing labour. Primary composite outcome: perinatal/neonatal mortality and/or serious neonatal morbidity. 2800 patients required to detect reduction of primary outcome from 4% to 2%. power 80%, 2-sided, α error of 0.05. A logistic model was used with generalized estimating equations to account for correlation between babies from the same pregnancy.
Results
2804 women randomized from 26 countries. 1398 to planned CS vs. 1406 to planned VB. There was no significant difference between treatment groups. Fifty seven babies of 2781 …
Scholar articles
J Barrett, E Aztalos, A Willan, K Joseph, BA Armson… - American Journal of Obstetrics & Gynecology, 2013