Authors
Jon FR Barrett, Mary E Hannah, Eileen K Hutton, Andrew N Willan, Alexander C Allen, B Anthony Armson, Amiram Gafni, KS Joseph, Dalah Mason, Arne Ohlsson, Susan Ross, J Johanna Sanchez, Elizabeth V Asztalos, Twin Birth Study Collaborative Group
Publication date
2015/6/1
Journal
Survey of Anesthesiology
Volume
59
Issue
3
Pages
131-132
Publisher
LWW
Description
Previous research suggests that CSE analgesia may offer more reliable catheter positioning, lower epidural catheter replacement rates, and a lower frequency of unilateral block compared with epidural analgesia alone. While quality evidence from trials does exist, that information needs systematic assessment. For the present study, researchers searched medical databases PubMed, EMBASE, CINAHL, LILACS, CENTRAL, and ISI WOS between June 2012 and February 2013, which returned 90 studies. The team systematically reviewed 10 randomized controlled trials comparing CSE analgesia and epidural block in 1722 woman in active labor.
A meta-analysis of the data found the relative risk (RR) of unilateral block was reduced after CSE analgesia compared with epidural analgesia at 0.48 (95% confidence interval [CI], 0.24–0.97). However, substantial nonuniformity between the studies was noted (I2= 69%, P …
Scholar articles
JFR Barrett, ME Hannah, EK Hutton, AN Willan… - Survey of Anesthesiology, 2015