Authors
Alexandre David, Kim G Larsen, Axel Legay, Marius Mikučionis, Danny Bøgsted Poulsen, Sean Sedwards
Publication date
2015/6
Journal
International journal on software tools for technology transfer
Volume
17
Pages
351-367
Publisher
Springer Berlin Heidelberg
Description
Statistical Model Checking (SMC) is a highly scalable simulation-based verification approach for testing and estimating the probability that a stochastic system satisfies a given linear temporal property. The technique has been applied to (discrete and continuous time) Markov chains, stochastic timed automata and most recently hybrid systems using the tool Uppaal SMC. In this paper we enable the application of SMC to complex biological systems, by combining Uppaal SMC with ANIMO, a plugin of the tool Cytoscape used by biologists, as well as with SimBiology®, a plugin of Matlab to simulate reactions. ANIMO and SimBiology® are two domain specific tools that have their own user interfaces and formalisms specifically tailored towards the biology domain. However—though providing means for simulation—both tools lack the powerful analytic capabilities offered by SMC, which in previous work have …
Total citations
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Scholar articles
A David, KG Larsen, A Legay, M Mikučionis… - International journal on software tools for technology …, 2015