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Abstract screening is one important aspect of conducting a high‐quality and comprehensive systematic review and meta‐analysis. Abstract screening allows the review team to conduct the tedious but vital first step to synthesize the extant literature: winnowing down the overwhelming amalgamation of citations discovered through research databases to the citations that should be “full‐text” screened and eventually included in the review. Although it is a critical process, few guidelines have been put forth since the publications of seminal systematic review textbooks. The purpose of this paper, therefore, is to provide a practical set of best practice guidelines to help future review teams and managers. Each of the 10 proposed guidelines is explained using real‐world examples or illustrations from applications. We also delineate recent experiences where a team of abstract screeners double‐screened 14 923 abstracts in …