Authors
Faith Matcham, Ian C Scott, Lauren Rayner, Matthew Hotopf, Gabrielle H Kingsley, Sam Norton, David L Scott, Sophia Steer
Publication date
2014/10/1
Source
Seminars in arthritis and rheumatism
Volume
44
Issue
2
Pages
123-130
Publisher
WB Saunders
Description
Objective
The assessment of health-related quality-of-life (HRQoL) in rheumatoid arthritis (RA) is becoming increasingly common in both research and clinical practice. One of the most widely used tools for measuring HRQoL is the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). We conducted a systematic review examining the impact of RA on HRQoL, measured through the SF-36.
Methods
MEDLINE and Embase were searched for observational studies reporting mean and standard deviation scores for each domain of the SF-36 in adult RA patients. Studies were reviewed in accordance with PRISMA guidelines, and a random-effects meta-analysis was performed.
Results
In total, 31 studies were eligible for inclusion in the meta-analysis, including 22,335 patients. Meta-analyses found that pooled mean HRQoL score for the SF-36 physical component summary was 34.1 (95% CI: 22.0–46.1) and …
Scholar articles
F Matcham, IC Scott, L Rayner, M Hotopf, GH Kingsley… - Seminars in arthritis and rheumatism, 2014