Authors
James B Galloway, Sam Norton, Richard D Barker, Andrew Brookes, Ivana Carey, Benjamin D Clarke, Raeesa Jina, Carole Reid, Mark D Russell, Ruth Sneep, Leah Sugarman, Sarah Williams, Mark Yates, James Teo, Ajay M Shah, Fleur Cantle
Publication date
2020/8/1
Journal
Journal of Infection
Volume
81
Issue
2
Pages
282-288
Publisher
WB Saunders
Description
Background
The COVID-19 pandemic continues to escalate. There is urgent need to stratify patients. Understanding risk of deterioration will assist in admission and discharge decisions, and help selection for clinical studies to indicate where risk of therapy-related complications is justified.
Methods
An observational cohort of patients acutely admitted to two London hospitals with COVID-19 and positive SARS-CoV-2 swab results was assessed. Demographic details, clinical data, comorbidities, blood parameters and chest radiograph severity scores were collected from electronic health records. Endpoints assessed were critical care admission and death. A risk score was developed to predict outcomes.
Findings
Analyses included 1,157 patients. Older age, male sex, comorbidities, respiratory rate, oxygenation, radiographic severity, higher neutrophils, higher CRP and lower albumin at presentation predicted critical …
Scholar articles
JB Galloway, S Norton, RD Barker, A Brookes, I Carey… - Journal of Infection, 2020