Authors
Jeanne M McCaffery, Andreana P Haley, Lawrence H Sweet, Suzanne Phelan, Hollie A Raynor, Angelo Del Parigi, Ron Cohen, Rena R Wing
Publication date
2009/10/1
Journal
The American journal of clinical nutrition
Volume
90
Issue
4
Pages
928-934
Publisher
Elsevier
Description
Background:Prior research indicates that successful weight-loss maintainers (SWLs) work harder than people of normal weight to maintain their weight loss, including greater dietary restriction of fat and higher physical activity levels. However, little work to date has examined how SWLs differ biologically from normal-weight (NW) and obese controls.
Objective:The objective was to compare the brain responses of SWLs to food pictures with those of NW and obese controls.
Design:Blood oxygen level–dependent responses to high- and low-energy food pictures were measured in 18 NW controls, 16 obese controls, and 17 SWLs.
Results:Group differences were identified in 4 regions, which indicated significant change in activation in response to the food pictures. SWLs showed greater activation in the left superior frontal region and right middle temporal region than did NW and obese controls—a pattern of results …
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JM McCaffery, AP Haley, LH Sweet, S Phelan… - The American journal of clinical nutrition, 2009