Authors
Nataliia Guz, Jan Halámek, James F Rusling, Evgeny Katz
Publication date
2014/5
Journal
Analytical and bioanalytical chemistry
Volume
406
Pages
3365-3370
Publisher
Springer Berlin Heidelberg
Description
The biocatalytic cascade based on enzyme-catalyzed reactions activated by several biomolecular input signals and producing output signal after each reaction step was developed as an example of a logically reversible information processing system. The model system was designed to mimic the operation of concatenated AND logic gates with optically readable output signals generated at each step of the logic operation. Implications include concurrent bioanalyses and data interpretation for medical diagnostics.
Figure
A biocatalytic cascade with several inputs–outputs was designed for bioanalytical applications providing responses with increasing levels of confidence
Scholar articles
N Guz, J Halámek, JF Rusling, E Katz - Analytical and bioanalytical chemistry, 2014