Authors
Maria Gamella, Nataliia Guz, José M Pingarrón, Roshanak Aslebagh, Costel C Darie, Evgeny Katz
Publication date
2015
Journal
Chemical Communications
Volume
51
Issue
36
Pages
7618-7621
Publisher
Royal Society of Chemistry
Description
A bioelectronic system composed of two modified electrodes, one activated in the presence of ketone bodies, a biomarker of diabetic ketoacidosis, and another releasing insulin upon receiving a signal, was designed and tested in vitro to operate as a Sense-and-Act device. The functional integration of biomarker-sensing and insulin-releasing electrodes represents a step to a theranostic system with autonomous operation.
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