Authors
Marion Tharrey, Francois Mariotti, Andrew Mashchak, Pierre Barbillon, Maud Delattre, Jean-François Huneau, Gary E Fraser
Publication date
2020/2/1
Journal
International Journal of Epidemiology
Volume
49
Issue
1
Pages
312-321
Publisher
Oxford University Press
Description
Background
The intake of specific amino acids (AA) has been associated with cardiovascular health, but amino acids are consumed together as dietary protein. Here we investigated the association between identified patterns of amino acid intake and cardiovascular mortality.
Methods
A total of 2216 cardiovascular deaths among 79 838 men and women from the Adventist Health Study-2 were included in our analysis. Baseline dietary patterns based on the participants' amino acids intakes were derived by factor analysis. Using Cox regression analyses, we estimated multivariate-adjusted hazard ratios (HRs) adjusted for sociodemographic and lifestyle factors and other dietary components.
Results
Three patterns of amino acids were identified. Factor 1 was positively associated with cardiovascular disease (CVD) mortality [hazard ratio (HR)Q5-Q1: 1.62, 98 …
Scholar articles
M Tharrey, F Mariotti, A Mashchak, P Barbillon… - International Journal of Epidemiology, 2020