Authors
Puneet Sharma, Josh Socolow, Salil Patel, Roderic I Pettigrew, John N Oshinski
Publication date
2006/3
Journal
Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine
Volume
23
Issue
3
Pages
323-330
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Purpose
To compare T1 values of blood and myocardium at 1.5T and 3T before and after administration of Gd‐DTPA‐BMA in normal volunteers, and to evaluate the distribution of contrast media between myocardium and blood during steady state.
Materials and Methods
Ten normal subjects were imaged with either 0.1 mmol/kg (N = 5) or 0.2 mmol/kg (N = 5) of Gd‐DTPA‐BMA contrast agent at 1.5T and 3T. T1 measurements of blood and myocardium were performed prior to contrast injection and every five minutes for 35 minutes following contrast injection at both field strengths. Measurements of biodistribution were calculated from the ratio of ΔR1R1myoR1blood).
Results
Precontrast blood T1 values (mean ± SD, N = 10) did not significantly differ between 1.5T and 3T (1.58 ± .13 sec, and 1.66 ± .06 sec, respectively; P > 0.05), but myocardium T1 values were significantly different (1.07 ± .03 sec and 1.22 ± …
Total citations
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Scholar articles
P Sharma, J Socolow, S Patel, RI Pettigrew… - Journal of Magnetic Resonance Imaging: An Official …, 2006