Authors
Raquel Jadulco, Ru Angelie Edrada, Rainer Ebel, Albrecht Berg, Karsten Schaumann, Victor Wray, Klaus Steube, Peter Proksch
Publication date
2004/1/23
Journal
Journal of Natural Products
Volume
67
Issue
1
Pages
78-81
Publisher
American Chemical Society
Description
The ethyl acetate extract of Penicillium sp., derived from the Mediterranean sponge Axinella verrucosa, yielded the known compound communesin B (1) and its new congeners communesins C (2) and D (3), as well as the known compounds griseofulvin, dechlorogriseofulvin, and oxaline. All structures were unambiguously established by 1D and 2D NMR and MS data. In several bioassays performed on different leukemia cell lines, the communesins exhibited moderate antiproliferative activity.
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Scholar articles
R Jadulco, RA Edrada, R Ebel, A Berg, K Schaumann… - Journal of Natural Products, 2004