Authors
Marco Pahor, Jack M Guralnik, Walter T Ambrosius, Steven Blair, Denise E Bonds, Timothy S Church, Mark A Espeland, Roger A Fielding, Thomas M Gill, Erik J Groessl, Abby C King, Stephen B Kritchevsky, Todd M Manini, Mary M McDermott, Michael E Miller, Anne B Newman, W Jack Rejeski, Kaycee M Sink, Jeff D Williamson, LIFE Study Investigators
Publication date
2014/6/18
Journal
Jama
Volume
311
Issue
23
Pages
2387-2396
Publisher
American Medical Association
Description
Importance
In older adults reduced mobility is common and is an independent risk factor for morbidity, hospitalization, disability, and mortality. Limited evidence suggests that physical activity may help prevent mobility disability; however, there are no definitive clinical trials examining whether physical activity prevents or delays mobility disability.
Objective
To test the hypothesis that a long-term structured physical activity program is more effective than a health education program (also referred to as a successful aging program) in reducing the risk of major mobility disability.
Design, Setting, and Participants
The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, randomized trial that enrolled participants between February 2010 and December 2011, who participated for an average of 2.6 years. Follow-up ended in December 2013. Outcome assessors were blinded to the intervention …
Total citations
Scholar articles
M Pahor, JM Guralnik, WT Ambrosius, S Blair… - Jama, 2014