Authors
Christina Magnussen, Teemu J Niiranen, Francisco M Ojeda, Francesco Gianfagna, Stefan Blankenberg, Erkki Vartiainen, Susana Sans, Gerard Pasterkamp, Maria Hughes, Simona Costanzo, Maria Benedetta Donati, Pekka Jousilahti, Allan Linneberg, Tarja Palosaari, Giovanni de Gaetano, Martin Bobak, Hester M den Ruijter, Torben Jørgensen, Stefan Söderberg, Kari Kuulasmaa, Tanja Zeller, Licia Iacoviello, Veikko Salomaa, Renate B Schnabel, BiomarCaRE Consortium
Publication date
2019/3
Journal
JACC: Heart Failure
Volume
7
Issue
3
Pages
204-213
Publisher
American College of Cardiology Foundation
Description
Objectives
This study investigates differences between women and men in heart failure (HF) risk and mortality.
Background
Sex differences in HF epidemiology are insufficiently understood.
Methods
In 78,657 individuals (median 49.5 years of age; age range 24.1 to 98.7 years; 51.7% women) from community-based European studies (FINRISK, DanMONICA, Moli-sani, Northern Sweden) of the BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in Europe) consortium, the association between incident HF and mortality, the relationship of cardiovascular risk factors, prevalent cardiovascular diseases, biomarkers (C-reactive protein [CRP]; N-terminal pro–B-type natriuretic peptide [NT-proBNP]) with incident HF, and their attributable risks were tested in women vs. men.
Results
Over a median follow-up of 12.7 years, fewer HF cases were observed in women (n = 2,399 [5.9%]) than in men (n = 2,771 [7.3%]). HF …
Scholar articles
C Magnussen, TJ Niiranen, FM Ojeda, F Gianfagna… - JACC: Heart Failure, 2019