View article

The clinical significance of Mycobacterium abscessus infection in the lung transplant population is not well understood.

An international survey was performed to determine the incidence and clinical outcomes of M abscessus infections before and after lung transplantation.

Thirty-one (50%) of the 62 transplant centers affiliated with the International Society of Heart and Lung Transplantation responded to the survey. Of 5,200 transplants performed, 17 patients (0.33%) (M/F, 12:5) were identified with M abscessus after transplantation. Two patients had respiratory colonization before lung transplantation. Post-transplantation M abscessus infections occurred in the pulmonary allograft in 12, in skin/soft tissue in 3, or both in 2. Median time to diagnosis after transplantation was 18.5 months (range, 1–111 months). Therapies included multiple antibiotics in 16, surgical débridement in …