Authors
David M Lee, Abdelouahid Tajar, Aslan Ulubaev, Neil Pendleton, Terence W O’neill, Daryl B O’connor, Gyorgy Bartfai, Steven Boonen, Roger Bouillon, Felipe F Casanueva, Joseph D Finn, Gianni Forti, Aleksander Giwercman, Thang S Han, Ilpo T Huhtaniemi, Krzysztof Kula, Michael EJ Lean, Margus Punab, Alan J Silman, Dirk Vanderschueren, Frederick CW Wu, Emas Study Group
Publication date
2009/7/1
Journal
Journal of Neurology, Neurosurgery & Psychiatry
Volume
80
Issue
7
Pages
722-729
Publisher
BMJ Publishing Group Ltd
Description
Background
Although there is evidence that vitamin D inadequacy may be linked to adverse cognitive outcomes, results from studies on this topic have been inconsistent. The aim of this trial was to examine the association between 25-hydroxyvitamin D (25(OH)D) levels and cognitive performance in middle-aged and older European men.
Methods
This population-based cross-sectional study included 3,369 men aged 40–79 years from eight centres enrolled in the European Male Ageing Study. Cognitive function was assessed using the Rey–Osterrieth Complex Figure (ROCF) test, the Camden Topographical Recognition Memory (CTRM) test and the Digit Symbol Substitution Test (DSST). Serum 25(OH)D levels were measured by radioimmunoassay. Additional assessments included measurement of physical activity, functional performance and mood/depression. Associations between cognitive function and 25(OH …
Total citations
Scholar articles
DM Lee, A Tajar, A Ulubaev, N Pendleton, TW O'neill… - Journal of Neurology, Neurosurgery & Psychiatry, 2009